Gene description for FASLG
Gene name	Fas ligand
Gene symbol	FASLG
Other names/aliases	ALPS1B APT1LG1 APTL CD178 CD95-L CD95L FASL TNFSF6 TNLG1A
Species	Homo sapiens
Experiment description of studies that identified FASLG in T cells
1 Experiment ID 91 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Western blotting PubMed ID 21252909    Organism Homo sapiens Experiment description Diacylglycerol kinase a regulates the formation and polarisation of mature multivesicular bodies involved in the secretion of Fas ligand-containing exosomes in T lymphocytes Authors Alonso R, Mazzeo C, Rodriguez MC, Marsh M, Fraile-Ramos A, Calvo V, Avila-Flores A, Merida I, Izquierdo M. Journal name CDD Publication year 2011 Sample T cells Sample name J-HM1-2.2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Lipids Methods used in the study Western blotting FACS Immunofluorescent microscopy EV-TRACK EV110031: EV-METRIC:22%
2 Experiment ID 273 Identified molecule protein Extracellular vesicle type Microvesicles MISEV EVs Identification method Western blotting PubMed ID 12021310    Organism Homo sapiens Experiment description Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles Authors Andreola G, Rivoltini L, Castelli C, Huber V, Perego P, Deho P, Squarcina P, Accornero P, Lozupone F, Lugini L, Stringaro A, Molinari A, Arancia G, Gentile M, Parmiani G, Fais S Journal name J Exp Med Publication year 2002 Sample T cells Sample name Jurkat Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
3 Experiment ID 292 Identified molecule protein Extracellular vesicle type Microvesicles MISEV EVs Identification method Western blotting FACS PubMed ID 10415024    Organism Homo sapiens Experiment description Activated human T cells release bioactive Fas ligand and APO2 ligand in microvesicles Authors Martíz-Lorenzo MJ, Anel A, Gamen S, Monle n I, Lasierra P, Larrad L, Piño A, Alava MA, Naval J Journal name J Immunol Publication year 1999 Sample T cells Sample name Jurkat - PHA stimulated Isolation/purification methods Differential centrifugation Ultracentrifugation FACS Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting FACS EV-TRACK -
4 Experiment ID 293 Identified molecule protein Extracellular vesicle type Microvesicles MISEV EVs Identification method Western blotting FACS PubMed ID 10415024    Organism Homo sapiens Experiment description Activated human T cells release bioactive Fas ligand and APO2 ligand in microvesicles Authors Martíz-Lorenzo MJ, Anel A, Gamen S, Monle n I, Lasierra P, Larrad L, Piño A, Alava MA, Naval J Journal name J Immunol Publication year 1999 Sample T cells Sample name T cell blasts Isolation/purification methods Differential centrifugation Ultracentrifugation FACS Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting FACS EV-TRACK -